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Melatonin has been shown to have anti-inflammatory effects, amongst a number of activities. Melatonin lowers tissue devastation during inflammatory responses by a variety of ways. Thus melatonin, by virtue of its capacity to directly feed on hazardous totally free radicals, lowers macromolecular damages in all organs. The free radicals and responsive oxygen as well as nitrogen species known to be fed on by melatonin include the highly harmful hydroxyl radical, peroxynitrite anion, as well as hypochlorous acid, to name a few. These agents all contribute to the inflammatory response and connected tissue devastation. Additionally, melatonin has other means to decrease the damage resulting from inflammation.
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